A decrease in the effectiveness of OCPs is a concern with coadministration of oral antibiotics. Although this concern has not been supported by research, some package inserts contain a warning about decreased OCP efficacy with concomitant ampicillin or tetracycline therapy. A review of pharmokinetic data showed a reduction of contraceptive steroid hormones only with concomitant use of rifampin (Rifadin). 24 [Evidence level B, nonquantitative systematic review] Nonetheless, it may be wise to inform patients receiving oral antibiotic therapy about the possibility of OCP failure, and to recommend the use of a second method of contraception.
Retin A is a very common acne treatment that many people use. This can lighten your skin. For your type of skin, I would consider a sensitive skin cleanser this will help decrease your inflammation that you might be getting with other products. Having a skin cleanser with salicylic acid 2% is vitally important. This ingredient will kill off bacteria that causes acne. A topical antibiotic cream with clindamycin can really help when things get really bad for you in terms of pustules and infections. A toner with salicylic acid can help after cleansing your skin with the cleanser above.
Diagnosis is based on the presence of comedones (pimples) and lesions at various stages of development. Left untreated, it can lead to both scarring and abnormal pigmentation.
It can be caused or exacerbated by elevated androgen levels. Androgen disturbances should be suspected when female adolescents have severe acne or when it persists into adult years, particularly when accompanied by other androgen-related effects such as hirsutism, infertility and weight problems.
If you have acne, hirsutism, or hair loss, these tests would be helpful in diagnosing the cause of your problems: serum levels of testosterone, DHEAS, LH, FSH, prolactin, cholesterol, triglycerides, and thyroid hormones. A two-hour glucose tolerance test with accompanying insulin levels should also be done.
Many PCOS women will have abnormal levels of one or more of these tests, although normal values do not rule out a diagnosis. Once your hormone imbalances are identified, the appropriate treatment can be recommended.