For beginners, the recommended dose of Sibutril 15mg is 15mg per day corresponding to one tablet. The ideal time to administer this drug is in the morning. The whole tablet of Sibutril 15mg should be taken with a glass of water or more and can be taken with or without food. The duration of the use should be prolonged up to 24 months to achieve a good result. It is noticed that users are not allowed to take double tablets of Sibutril 15mg at the same time because of its cause of adverse effects.
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Metabolic effects occurring during anabolic steroid therapy in immobilized patients or those with metastatic breast disease include osteolytic-induced hypercalcemia.
Anabolic steroids effect electrolyte balance, nitrogen retention, and urinary calcium excretion. Edema, with and without congestive heart failure, has occurred during anabolic steroid therapy.
The androgenic activity of anabolic steroids may decrease levels of thyroxin-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction.
Significant increases in low density lipoproteins (LDL) and decreases in high density lipoproteins (HDL) have occurred. [ Ref ]