Corticosteroid nasal sprays brands

An allergy occurs when the body reacts to foreign particles it can't tolerate. These particles, such as tree pollen or dust mites, are called antigens, or allergens, and are normally harmless. But the immune system of a person with allergies views the allergens as harmful. Following the body’s first contact with an allergen, white blood cells produce antibodies that prepare the immune system for the same allergen the next time it enters the body. Antibodies attach themselves to cells such as basophils and mast cells. Later contact with even a small amount of the allergen triggers the cells to release chemicals such as leukotrienes, prostaglandins, and histamine. When these chemicals are released, they attach to the receptors of nearby cells. The binding causes swelling of nasal blood vessels and inflammation of membranes. This results in common allergy symptoms such as: • sneezing • itchiness • watery nose • and congestion Normally to reduce inflammation, the brain signals the adrenal glands to produce a hormone called cortisol. Cortisol works against allergens by acting on receptors in the cytoplasm of various cells. Once bound, cortisol-receptor complex enters into the nucleus. There it binds to the DNA and prevents the creation of proteins responsible for the release of inflammatory chemicals. As a result, when the allergen binds to the antibodies on the cell, the cell is not triggered to release inflammatory chemicals. Sometimes cortisol is not able to control the immune system response. In this case, nasal corticosteroids, synthetically-produced hormones similar to cortisol, may be prescribed. When inhaled, they bind to receptors and the complex works in the same way as cortisol. Therefore, when the allergen binds to the antibodies on the cell, the inflammatory chemicals are not released. As a result, the immune system’s response is decreased and symptoms are reduced. While effective, corticosteroids are not right for everyone and can cause minor as well as serious side effects, so a corticosteroid therapy should only be started under the care and guidance of a physician.

Decongestant nasal sprays are available over-the-counter in many countries. They work to very quickly open up nasal passages by constricting blood vessels in the lining of the nose. Prolonged use of these types of sprays can damage the delicate mucous membranes in the nose. This causes increased inflammation, an effect known as rhinitis medicamentosa or the rebound effect . Decongestant nasal sprays are advised for short-term use only, preferably 5 to 7 days at maximum. Some doctors advise to use them 3 days at maximum. A recent clinical trial has shown that a corticosteroid nasal spray may be useful in reversing this condition. [3] Topical nasal decongestants include:

Mild nasopharyngeal irritation following the use of beclomethasone aqueous nasal spray has been reported in up to 24% of patients treated, including occasional sneezing attacks (about 4%) occurring immediately following use of the spray. In patients experiencing these symptoms, none had to discontinue treatment. The incidence of transient irritation and sneezing was approximately the same in the group of patients who received placebo in these studies, implying that these complaints may be related to vehicle components of the formulation.

If allergies are responsible for post-nasal drip, over-the counter antihistamines (., loratadine, desloratadine, cetirizine, fexofenadine) can be used to help with symptoms. Talk to your doctor or pharmacist before starting an antihistamine. Your doctor may also prescribe a corticosteroid nasal spray (., budesonide, fluticasone, mometasone) to help. Avoiding the allergies that cause runny noses can prevent post-nasal drip from happening again. Many people are allergic only during certain seasons or times of the year, mostly to pollens, moulds, or weeds. Year-round causes of allergies include mites, animal dander, and moulds.

Corticosteroid nasal sprays brands

corticosteroid nasal sprays brands

If allergies are responsible for post-nasal drip, over-the counter antihistamines (., loratadine, desloratadine, cetirizine, fexofenadine) can be used to help with symptoms. Talk to your doctor or pharmacist before starting an antihistamine. Your doctor may also prescribe a corticosteroid nasal spray (., budesonide, fluticasone, mometasone) to help. Avoiding the allergies that cause runny noses can prevent post-nasal drip from happening again. Many people are allergic only during certain seasons or times of the year, mostly to pollens, moulds, or weeds. Year-round causes of allergies include mites, animal dander, and moulds.

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